Sachiko abe biography channel
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Abstract
G-protein-gated K+ (KG) channels generate slow inhibitory postsynaptic potentials in the brain. Current opinion suggests that neuronal KG channels are heterotetramers of Kir3.1 and Kir3.2. In substantia nigra (SN), however, mRNA of Kir3.1 does not express, whereas that of Kir3.2 clearly does. Therefore, we have characterized the KGchannels containing Kir3.2 subunits in SN using biochemical and immunological techniques. We found that they were composed of only Kir3.2 subunits and did not contain significant amounts of either Kir3.1 or Kir3.3. Furthermore, at least some of the KGchannels in SN were assemblies of the splicing variants Kir3.2a and Kir3.2c. The channels were localized specifically at the postsynaptic membrane on the dendrites of dopaminergic neurons. Kir3.2c, but not Kir3.2a, could bind a PDZ domain-containing protein, PSD-95. The heterologously expressed KG channels composed of Kir3.2a plus Kir3.2c or Kir3.2a alone were activated by G-protein stimulation, but expression of Kir3.2c alone was not. This study reveals that the Kir3.2 splicing variants play distinct roles in the control of function and localization of some of the KG channels in dopaminergic neurons of SN.
Keywords: substantia nigra, G-protein, inwardly rectifying potassium ch
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Artists
This is a list thoroughgoing artists bang into work cut down the MOMAT's collection. Produce revenue is updated continually.
A
ABAKANOWICZ, Magdalena
ABAKANOWICZ, River
1930–2017
ABBOTT, Berenice
ABBOTT, Berenice
1898–1991
ABE, Gosei
ABE, Gosei
1910–1972
ABE, Nobuya (Yoshibumi)
ABE, Nobuya (Yoshibumi)
1913–1971
ABE, Shumpo
ABE, Shumpo
1877–1956
ACCONCI, Vito
ACCONCI, Vito
1940–2017
ADACHI, Gen'ichiro
ADACHI, Gen’ichiro
1889–1973
ADAM, Henri Georges
Mdma, Henri Georges
1904–1967
ADAMCZYK Junior, Frank / HUTTER, R.R. / Comic, D.T. / WYLDER, Identification (Southern Algonquian Universitiy)
ADAMCZYK Jr., Unclothed / HUTTER, R.R. / MOORE, D.T. / WYLDER, Mark (Southern Illinois Universitiy)
ADAMS, Ansel
ADAMS, Ansel
1902–1984
ADAMSON, PRESCOTT
ADAMSON, Town
1866–1933
AI-MITSU
AI-MITSU
1907–1946
AI-O
AI-O
1931–
AIDA, Makoto
AIDA, Makoto
1965–
AIGASA, Masayoshi
AIGASA, Masayoshi
1939–
AKABORI, Shimpei
AKABORI, Shimpei
1899–1992
AKAGI, Yasunobu
AKAGI, Yasunobu
1889–1955
AKAMATSU, Unrei
AKAMATSU, Unrei
1892–1958
AKANA, Hiroshi
AKANA, Hiroshi
1922–2009
AKASEGAWA, Gempei
AKASEGAWA, Gempei
1937–2014
AKASEGAWA, Gempei et al.
AKASEGAWA, Gempei et assurance.
AKATSUKA, Yuji
AKATSUKA, Yuji
1955–
AKINO, Fuku
AK
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Kōhaku Uta Gassen
Japanese New Year's Eve musical television special
For the recent event, see 75th NHK Kōhaku Uta Gassen. For the upcoming event, see 76th NHK Kōhaku Uta Gassen.
NHK Kōhaku Uta Gassen (Japanese: NHK紅白歌合戦, Hepburn: Enu Eichi Kei Kōhaku Uta Gassen, "NHK Red and White Song Battle"[1]), more commonly known simply as Kōhaku, is an annual New Year's Evetelevision special produced by Japanese public broadcaster NHK. It is broadcast live simultaneously on television and radio, nationally and internationally by the NHK network and by some overseas (mainly cable) broadcasters who buy the program. The show ends shortly before midnight. Before the show began broadcasting on television in late 1953, the show was held on 3 January and only consisted of a radio broadcast.
The program divides the most popular music artists of the year into competing teams of red and white. The "red" team or akagumi (赤組, 紅組) is composed of all female artists (or groups with female vocals), while the "white" team or shirogumi (白組) is all male (or groups with male vocals). At the end of the show, judges and the audience vote to decide which group performed better.[2] The honor of performing on Kōhaku is strictly by invitation, so only the most successfu